| in order to conserve energy | 5 | purpose |
| at their active sites | 3 | location |
| during catalysis | 3 | temporal |
| enzyme → contain → copper | 12 |
| enzyme → require → copper | 9 |
| enzyme → use → copper | 4 |
| enzyme → employ → copper | 4 |
| negative | neutral | positive |
| 0.048 | 0.853 | 0.099 |
| Raw frequency | 29 |
| Normalized frequency | 0.413 |
| Modifier score | 0.500 |
| Perplexity | 205.119 |