intravenous amiodarone
(subgroup of
amiodarone)
→
IsA
→
bolus dose amiodarone
|
0.68
|
|
effect
(aspect of
amiodarone)
→
HasProperty
→
reversible
|
0.68
|
|
metabolite
(aspect of
amiodarone)
→
ReceivesAction
→
excreted in human milk
|
0.68
|
|
potential
(aspect of
amiodarone)
→
CapableOf
→
inhibit cyp2c9
|
0.68
|
|
amiodarone
→
HasProperty
→
effective
|
0.59
|
|
amiodarone
→
IsA
→
the drug
|
0.58
|
|
amiodarone
→
ReceivesAction
→
administered
|
0.56
|
|
amiodarone
→
ReceivesAction
→
discontinued
|
0.52
|
|
effect
(aspect of
amiodarone)
→
CapableOf
→
become prominent
|
0.51
|
|
effect
(aspect of
amiodarone)
→
ReceivesAction
→
studied in 30 healthy subjects
|
0.51
|
|
amiodarone
→
ReceivesAction
→
started
|
0.50
|
|
amiodarone
→
CapableOf
→
cross the placenta
|
0.47
|
|
amiodarone
→
HasProperty
→
safe
|
0.46
|
|
amiodarone
→
Causes
→
hyperthyroidism
|
0.41
|
|
amiodarone
→
HasProperty
→
suitable
|
0.41
|
|
amiodarone
→
CapableOf
→
prevent recurrence of atrial fibrillation
|
0.41
|
|
amiodarone
→
HasProperty
→
toxic
|
0.38
|
|
amiodarone
→
HasProperty
→
unavailable
|
0.36
|
|
amiodarone
→
Causes
→
side effects
|
0.35
|
|
amiodarone
→
Causes
→
either hypothyroidism
|
0.35
|
|
amiodarone
→
HasProperty
→
dialyzable
|
0.35
|
|
amiodarone
→
Causes
→
bradycardia
|
0.32
|
|
amiodarone
→
ReceivesAction
→
avoided in pregnant patient
|
0.32
|
|
amiodarone
→
CapableOf
→
inhibit cyp3a4 activity
|
0.32
|
|
amiodarone
→
CapableOf
→
inhibit co
|
0.32
|
|
amiodarone
→
ReceivesAction
→
continued
|
0.31
|
|
amiodarone
→
HasSubevent
→
higher rate of survival
|
0.31
|
|
amiodarone
→
CapableOf
→
take with procainamide
|
0.31
|
|
effect
(aspect of
amiodarone)
→
HasProperty
→
fatal
|
0.29
|
|
amiodarone
→
ReceivesAction
→
compared to placebo
|
0.28
|
|
medicine
→
HasA
→
amiodarone
|
0.28
|
|
amiodarone
→
CapableOf
→
prolong phase
|
0.25
|
|
amiodarone
→
ReceivesAction
→
compared with lidocaine
|
0.25
|
|
amiodarone
→
HasProperty
→
superior
|
0.25
|
|
amiodarone
→
IsA
→
benzofuran derivative
|
0.25
|
|
amiodarone
→
CapableOf
→
reduce scd
|
0.25
|
|
metabolite
(aspect of
amiodarone)
→
CapableOf
→
cross the placenta
|
0.25
|
|
potential
(aspect of
amiodarone)
→
CapableOf
→
inhibit cyp3a
|
0.25
|
|
potential
(aspect of
amiodarone)
→
CapableOf
→
inhibit organic cation transporter
|
0.25
|
|
amiodarone
→
ReceivesAction
→
stopped
|
0.23
|
|
amiodarone
→
ReceivesAction
→
excreted
|
0.23
|
|
amiodarone
→
HasProperty
→
helpful
|
0.16
|
|
amiodarone
→
Causes
→
heart block
|
0.16
|
|
amiodarone
→
CapableOf
→
caused sinus arrest
|
0.16
|
|
amiodarone
→
CapableOf
→
cause thyroid problems
|
0.16
|
|
amiodarone
→
Causes
→
pulmonary fibrosis
|
0.16
|
|
amiodarone
→
HasSubevent
→
increased exposure
|
0.16
|
|
amiodarone
→
CapableOf
→
keep the heart
|
0.16
|
|
potential
(aspect of
amiodarone)
→
CapableOf
→
cause serious side effects
|
0.16
|
|