---

nicotine (aspect of cigarette) → HasProperty → addictive	0.75
nicotine (aspect of tobacco) → HasProperty → addictive	0.75
e cigarette (subgroup of cigarette) → HasA → nicotine	0.73
e juice (subgroup of juice) → HasA → nicotine	0.68
nicotine → ReceivesAction → absorbed	0.68
cigarette → HasA → nicotine	0.67
electronic cigarette (subgroup of cigarette) → HasA → nicotine	0.64
tobacco → HasA → nicotine	0.61
aerosol → HasA → nicotine	0.60
nicotine → IsA → stimulant	0.57
nicotine → ReceivesAction → released	0.56
nicotine → ReceivesAction → inhaled	0.56
juice → HasA → nicotine	0.53
nicotine → HasA → product	0.52
nicotine (aspect of cigarette) → HasA → product	0.52
nicotine → AtLocation → tobacco	0.52
nicotine → AtLocation → cigarette	0.51
nicotine → ReceivesAction → used as insecticide	0.50
product → HasA → nicotine	0.50
nicotine → ReceivesAction → added	0.50
nicotine → CapableOf → enter the bloodstream	0.48
nicotine → HasA → electronic cigarettes	0.48
nicotine → CapableOf → enter the body	0.47
nicotine → ReceivesAction → metabolized into cotinine	0.47
nicotine → ReceivesAction → metabolized in the liver	0.47
nicotine → HasProperty → addictive	0.46
nicotine → HasA → negative effects	0.46
nicotine → IsA → alkaloid	0.45
nicotine → CapableOf → reach the brain	0.45
effect (aspect of nicotine) → HasProperty → temporary	0.45
refill → HasA → nicotine	0.44
nicotine → ReceivesAction → extracted	0.43
nicotine → ReceivesAction → dissolved in propylene glycol	0.43
nicotine → HasProperty → detectable	0.43
nicotine → AtLocation → tobacco leaves	0.43
nicotine → CapableOf → pass into the bloodstream	0.43
nicotine (aspect of cigarette) → CapableOf → enter the body	0.42
nicotine → CapableOf → stimulate the release of dopamine	0.42
nicotine → ReceivesAction → derived	0.42
nicotine → HasProperty → toxic	0.41
effect (aspect of nicotine) → HasProperty → mild	0.41
nicotine → CapableOf → stimulate the brain	0.41
nicotine → ReceivesAction → diluted	0.41
effect (aspect of nicotine) → ReceivesAction → reduced	0.41
effect (aspect of nicotine) → ReceivesAction → studied	0.41
nicotine → HasProperty → harmful	0.41
nicotine → IsA → drug	0.41
nicotine → CapableOf → increase blood pressure	0.41
nicotine → ReceivesAction → removed	0.40
nicotine → CapableOf → bind to receptor	0.40
nicotine (aspect of cigarette) → IsA → stimulant	0.40
nicotine → CapableOf → bind to nicotinic acetylcholine receptors	0.39
nicotine → HasProperty → poisonous	0.39
effect (aspect of nicotine) → HasProperty → unknown	0.39
effect (aspect of nicotine) → CapableOf → last	0.39
nicotine → CapableOf → increase heart rate	0.39
nicotine (aspect of tobacco) → CapableOf → enter the body	0.39
nicotine (aspect of tobacco) → IsA → stimulant	0.39
nicotine → HasProperty → dangerous	0.39
cigar → HasA → nicotine	0.38
nicotine → ReceivesAction → absorbed through the skin	0.38
nicotine → ReceivesAction → absorbed into the bloodstream	0.38
nicotine (aspect of cigarette) → ReceivesAction → used as insecticide	0.38
nicotine → ReceivesAction → handled with care	0.38
nicotine → Causes → addiction	0.37
nicotine → IsA → powerful drug	0.37
effect (aspect of nicotine) → HasProperty → minimal	0.37
effect (aspect of nicotine) → HasProperty → short-lived	0.37
nicotine (aspect of cigarette) → ReceivesAction → intended for human consumption	0.37
nicotine → ReceivesAction → metabolized	0.36
nicotine → ReceivesAction → delivered by cigarette	0.36
nicotine → Causes → cancer	0.36
effect (aspect of nicotine) → HasProperty → harmful	0.36
smoker → Desires → nicotine	0.36
nicotine (aspect of tobacco) → HasProperty → toxic	0.36
nicotine (aspect of tobacco) → ReceivesAction → absorbed	0.36
nicotine (aspect of cigarette) → CapableOf → reach the brain	0.35
nicotine → HasProperty → bad	0.35
nicotine → IsA → the substance	0.34
nicotine → ReceivesAction → consumed	0.34
nicotine (aspect of tobacco) → HasA → pharmacologic effects	0.34
nicotine → CapableOf → promote tumor growth	0.34
nicotine → ReceivesAction → produced	0.34
nicotine → ReceivesAction → associated with cigarette	0.34
nicotine → CapableOf → improve concentration	0.33
nicotine → CapableOf → affect the brain	0.33
product (aspect of customer) → HasA → nicotine	0.33
nicotine (aspect of cigarette) → HasProperty → toxic	0.33
nicotine (aspect of cigarette) → IsA → drug	0.33
nicotine → ReceivesAction → absorbed by lung	0.33
nicotine → CapableOf → affect memory	0.33
nicotine → AtLocation → nightshade family of plants	0.33
nicotine → HasA → effect	0.32
nicotine → HasA → benefit	0.32
nicotine (aspect of cigarette) → CapableOf → take over the reward pathways	0.32
nicotine (aspect of cigarette) → ReceivesAction → released	0.32
effect (aspect of nicotine) → HasProperty → significant	0.32
nicotine → CapableOf → stimulate the physique	0.32
nicotine → ReceivesAction → dissolved in water	0.32
nicotine → ReceivesAction → absorbed through the mouth	0.31
smoke → HasA → nicotine	0.31
nicotine (aspect of tobacco) → CapableOf → employ a heating element	0.31
nicotine → CapableOf → give hard time	0.31
nicotine (aspect of tobacco) → IsA → the substance	0.31
product (aspect of manufacturer) → HasA → nicotine	0.31
nicotine → CapableOf → constrict blood vessels	0.31
nicotine → HasA → similar effects	0.30
nicotine → HasProperty → mutagenic	0.30
nicotine → CapableOf → act as sedative	0.30
nicotine → CapableOf → activate receptor	0.30
nicotine → CapableOf → suppress appetite	0.30
nicotine (aspect of tobacco) → ReceivesAction → absorbed into the bloodstream	0.30
nicotine (aspect of cigarette) → AtLocation → cigarette	0.30
nicotine → HasProperty → effective	0.29
nicotine → CapableOf → kill human	0.29
nicotine → CapableOf → leave the body	0.29
nicotine → HasProperty → safe	0.29
nicotine → CapableOf → reduce stress	0.29
nicotine → HasProperty → pure	0.29
nicotine → AtLocation → tomato	0.29
nicotine → CapableOf → stimulate adrenal glands	0.29
nicotine → HasA → harmful effects	0.29
nicotine → CapableOf → harm brain development	0.29
nicotine (aspect of tobacco) → CapableOf → induce sox2	0.29
nicotine (aspect of tobacco) → ReceivesAction → used as insecticide	0.29
nicotine (aspect of tobacco) → ReceivesAction → extracted	0.29
nicotine (aspect of tobacco) → AtLocation → tobacco	0.29
nicotine → ReceivesAction → associated with cardiovascular disease	0.28
nicotine → CapableOf → enter lung	0.28
nicotine → CapableOf → pass into breast milk	0.28
nicotine → HasProperty → lethal	0.28
effect (aspect of nicotine) → HasProperty → strong	0.28
nicotine → HasProperty → harmless	0.28
nicotine (aspect of cigarette) → Causes → addiction	0.28
nicotine (aspect of cigarette) → ReceivesAction → metabolized	0.28
nicotine → CapableOf → improve attention	0.28
nicotine → ReceivesAction → delivered to the body	0.27
nicotine → CapableOf → cross the blood-brain barrier	0.27
nicotine → HasProperty → tasteless	0.27
nicotine → CapableOf → interact with certain pharmaceutical drugs	0.27
nicotine → CapableOf → reduce the craving	0.27
nicotine → ReceivesAction → withdrawn	0.27
nicotine → ReceivesAction → desired to produce favorable effects	0.27
nicotine → CapableOf → kill child	0.27
nicotine (aspect of cigarette) → AtLocation → tobacco	0.27
nicotine (aspect of cigarette) → CapableOf → constrict blood vessels	0.27
nicotine (aspect of cigarette) → Causes → cancer	0.27
nicotine (aspect of cigarette) → ReceivesAction → absorbed	0.27
nicotine → CapableOf → reduce blood flow	0.26
nicotine → CapableOf → stimulate nervous system	0.26
nicotine → CapableOf → affect the body	0.26
nicotine → CapableOf → increase alertness	0.26
nicotine → HasProperty → important	0.26
nicotine → IsA → vasoconstrictor	0.26
nicotine → CapableOf → reduce anxiety	0.26
nicotine → IsA → a central nervous system stimulant	0.25
nicotine → CapableOf → promote migration	0.25
nicotine → CapableOf → induce cell proliferation	0.25
nicotine → CapableOf → affect neurotransmitter	0.25
nicotine → HasProperty → soluble	0.25
nicotine → AtLocation → eggplant	0.25
nicotine → CapableOf → enhance haemodynamic effects of adenosine	0.25
nicotine → CapableOf → increase pain response	0.25
nicotine → ReceivesAction → delivered per puff	0.25
nicotine → CapableOf → activate reward pathways	0.25
nicotine → AtLocation → potato	0.25
nicotine → CapableOf → increase lipolysis	0.25
nicotine → Causes → animal	0.25
nicotine → CapableOf → remain detectable	0.25
nicotine → ReceivesAction → vaporized	0.25
nicotine → CapableOf → hit the brain	0.25
nicotine → ReceivesAction → heated	0.25
nicotine → HasProperty → optional	0.25
nicotine → ReceivesAction → delivered without smoke	0.25
nicotine → ReceivesAction → retained by the user	0.25
nicotine → CapableOf → seek in rat	0.25
nicotine → CapableOf → vary within single variety	0.25
nicotine → CapableOf → turn gelatinous	0.25
nicotine → ReceivesAction → allowed to warm up before use	0.25
nicotine → CapableOf → create vapor	0.25
nicotine → CapableOf → stimulate fibroblast proliferation	0.25
nicotine → ReceivesAction → eliminated by the kidney	0.25
nicotine → ReceivesAction → excreted as unchanged drug	0.25
nicotine → ReceivesAction → administered for 5 consecutive days	0.25
nicotine → CapableOf → inhibit apoptosis	0.25
effect (aspect of nicotine) → HasProperty → reversible	0.25
effect (aspect of nicotine) → HasProperty → rare	0.25
effect (aspect of nicotine) → HasProperty → more pronounced	0.25
effect (aspect of nicotine) → HasProperty → immediate	0.25
effect (aspect of nicotine) → SimilarTo → other popular drug	0.25
effect (aspect of nicotine) → HasProperty → controversial	0.25
nicotine (aspect of cigarette) → CapableOf → provide depressant effect	0.25
nicotine (aspect of cigarette) → CapableOf → stimulate adrenal glands	0.25
nicotine (aspect of cigarette) → CapableOf → exert sedative effect	0.25
nicotine (aspect of tobacco) → CapableOf → provide both a stimulant	0.25
nicotine (aspect of tobacco) → CapableOf → provide depressant effect	0.25
nicotine (aspect of cigarette) → ReceivesAction → dissolved in water	0.25
nicotine (aspect of tobacco) → ReceivesAction → removed	0.25
nicotine (aspect of tobacco) → IsA → drug	0.25
nicotine → CapableOf → improve mood	0.25
nicotine (aspect of cigarette) → CapableOf → increase blood pressure	0.24
nicotine (aspect of cigarette) → Causes → heart problems	0.24
nicotine (aspect of cigarette) → HasProperty → harmful	0.24
nicotine → IsA → both a stimulant	0.24
nicotine → CapableOf → harm unborn baby	0.24
nicotine → CapableOf → suppress insulin output	0.24
effect (aspect of nicotine) → HasProperty → severe	0.23
nicotine → CapableOf → cross the placenta	0.23
nicotine → CapableOf → increase the risk	0.23
nicotine → CapableOf → induce angiogenesis	0.23
nicotine → HasProperty → more addictive than heroin	0.23
nicotine → HasA → liquid	0.23
nicotine → HasProperty → legal	0.23
nicotine → Causes → change	0.23
nicotine → CapableOf → avoid the symptoms of withdrawal	0.23
nicotine (aspect of tobacco) → Causes → cancer	0.23
nicotine (aspect of tobacco) → HasA → product	0.23
nicotine → HasProperty → concentrated	0.22
nicotine → ReceivesAction → used to help adult	0.22
nicotine → ReceivesAction → classified in the poisons standard	0.22
nicotine → CapableOf → kill dog	0.22
nicotine → HasProperty → carcinogenic	0.22
nicotine → CapableOf → affect the way	0.22
nicotine (aspect of cigarette) → ReceivesAction → inhaled	0.21
nicotine → Causes → nausea	0.21
nicotine → ReceivesAction → exposed to air	0.20
nicotine → Causes → irritation	0.20
nicotine → CapableOf → affect learning	0.20
nicotine → HasProperty → more potent	0.20
nicotine → CapableOf → cause lung cancer	0.20
nicotine → ReceivesAction → classified as stimulant	0.20
nicotine → Causes → seizure	0.20
nicotine (aspect of tobacco) → HasProperty → colorless	0.20
nicotine → CapableOf → be a gateway drug	0.19
effect (aspect of nicotine) → HasProperty → dangerous	0.19
nicotine (aspect of cigarette) → CapableOf → damage lung	0.19
nicotine (aspect of cigarette) → CapableOf → cross the placenta	0.19
nicotine (aspect of cigarette) → Causes → a release of dopamine	0.19
nicotine (aspect of cigarette) → HasA → immediate satisfying experience	0.19
nicotine → ReceivesAction → associated with potential birth defects	0.18
nicotine → ReceivesAction → associated with poisoning	0.18
nicotine → CapableOf → promote invasion	0.18
nicotine → AtLocation → all tobacco products	0.18
nicotine → ReceivesAction → delivered to lung	0.18
nicotine → CapableOf → keep smoker	0.18
nicotine → ReceivesAction → sprayed into each nostril	0.18
nicotine → CapableOf → come into contact	0.18
nicotine → CapableOf → act as depressant	0.18
nicotine → Causes → headache	0.18
nicotine → ReceivesAction → avoided	0.18
nicotine → CapableOf → reach peak levels	0.18
nicotine → Causes → dizziness	0.16
nicotine → AtLocation → cigar	0.16
nicotine → CapableOf → smoke cigarette	0.16
nicotine → Causes → insulin resistance	0.16
nicotine → HasProperty → colorless	0.16
nicotine → HasA → the most effect	0.16
nicotine → CapableOf → slow the progression of disease	0.16
nicotine → ReceivesAction → administrated by oral tobacco products	0.16
nicotine → HasSubevent → indigestion	0.16
nicotine → HasSubevent → heartburn	0.16
nicotine → CapableOf → provide immediate kick	0.16
nicotine → CapableOf → chew tobacco	0.16
nicotine → CapableOf → relax muscle	0.16
nicotine → ReceivesAction → absorbed through the smoke	0.16
nicotine → CapableOf → leave craving	0.16
nicotine → AtLocation → chewing tobacco	0.16
nicotine → ReceivesAction → given by other means	0.16
nicotine → HasProperty → strong	0.16
nicotine → CapableOf → remain addictive	0.16
nicotine → Causes → dna damage	0.16
nicotine → IsA → toxic alkaloid	0.16
nicotine → ReceivesAction → inhaled by child	0.16
nicotine → ReceivesAction → administered to mouse	0.16
nicotine → Causes → emphysema	0.16
nicotine → CapableOf → help fight depression	0.16
nicotine → Causes → physical dependence	0.16
nicotine → CapableOf → turn brown	0.16
nicotine → CapableOf → affect maternal and fetal health	0.16
nicotine → Causes → death	0.16
nicotine → CapableOf → increase atrial vulnerability	0.16
nicotine → ReceivesAction → absorbed through gum	0.16
nicotine → IsA → known poison	0.16
effect (aspect of nicotine) → HasProperty → mental	0.16
effect (aspect of nicotine) → HasProperty → serious	0.16
nicotine (aspect of cigarette) → CapableOf → increase heart rate	0.16
nicotine (aspect of cigarette) → CapableOf → kill human	0.16
nicotine (aspect of cigarette) → CapableOf → affect maternal and fetal health	0.16
nicotine (aspect of cigarette) → CapableOf → reach peak levels	0.16
nicotine (aspect of cigarette) → CapableOf → suppress insulin output	0.16
nicotine (aspect of tobacco) → CapableOf → reach peak levels	0.16
nicotine (aspect of cigarette) → HasA → direct adverse effect	0.16
nicotine (aspect of cigarette) → HasProperty → unhealthy	0.16
nicotine (aspect of tobacco) → HasProperty → high	0.16
nicotine (aspect of cigarette) → ReceivesAction → measured by smoking machines	0.16
nicotine (aspect of cigarette) → ReceivesAction → associated with potential birth defects	0.16
nicotine (aspect of cigarette) → ReceivesAction → associated with poisoning	0.16
cigarette → HasSubevent → nicotine	0.16
effect (aspect of nicotine) → ReceivesAction → documented	0.16
nicotine → ReceivesAction → left in the body	0.09