| on the transmission | 8 | transitive-object |
| on gene expression | 7 | transitive-object |
| on the protein’s function | 6 | transitive-object |
| mutation → have → impact | 33 |
| mutation → have → significant impact | 10 |
| mutation → have → major impact | 5 |
| mutation → have → what impact | 3 |
| mutation → have → influence | 3 |
| mutation → have → major effect | 3 |
| negative | neutral | positive |
| 0.213 | 0.724 | 0.063 |
| Raw frequency | 57 |
| Normalized frequency | 0.596 |
| Modifier score | 0.633 |
| Perplexity | 138.514 |