| to treatment | 18 | cause |
| as a next therapeutic step | 7 | purpose |
| generally | 6 | degree |
| symptom → be → resistant | 25 |
| symptom → become → resistant | 4 |
| symptom → be → treatment-resistant | 4 |
| negative | neutral | positive |
| 0.475 | 0.385 | 0.139 |
| Raw frequency | 33 |
| Normalized frequency | 0.323 |
| Modifier score | 0.600 |
| Perplexity | 188.187 |